- 专利标题： Methyl- and Trifluoromethyl-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof
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申请号： US15889296申请日： 2018-02-06
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公开(公告)号： US20180170928A1公开(公告)日： 2018-06-21
- 发明人: MARK EDWARD SCHNUTE , ANDREW CHRISTOPHER FLICK , PETER JONES , NEELU KAILA , SCOT RICHARD MENTE , JOHN DAVID TRZUPEK , MICHAEL L. VAZQUEZ , GORAN MATTIAS WENNERSTAL , LI XING , EDOUARD ZAMARATSKI , LIYING ZHANG
- 申请人： Pfizer Inc.
- 申请人地址： US NY New York
- 专利权人： Pfizer Inc.
- 当前专利权人： Pfizer Inc.
- 当前专利权人地址： US NY New York
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D401/14
摘要：
The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.
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