专利检索 ap:("Pfizer Inc.") AND inv:"MARK EDWARD SCHNUTE" 第 1 页

1.

发明申请
Methyl- and Trifluoromethyl-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof 审中-公开
标题翻译： RORC2的甲基和三氟甲基取代的吡咯并吡啶调节剂及其使用方法

公开(公告)号：US20160090381A1

公开(公告)日：2016-03-31

申请号：US14864840

申请日：2015-09-24

申请人： Pfizer Inc.

发明人： MARK EDWARD SCHNUTE , ANDREW CHRISTOPHER FLICK , PETER JONES , NEELU KAILA , SCOT RICHARD MENTE , JOHN DAVID TRZUPEK , MICHAEL L. VAZQUEZ , GÖRAN MATTIAS WENNERSTÅL , LI XING , EDOUARD ZAMARATSKI , LIYING ZHANG

IPC分类号： C07D471/04

CPC分类号： C07D471/04 , C07D401/14

摘要： The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.

摘要翻译： 本发明提供甲基 - 和三氟甲基取代的吡咯并吡啶，其药物组合物，调节受试者的RORγ活性和/或减少IL-17的量的方法，以及使用这种吡咯并吡啶治疗各种医学病症的方法及其药物组合物。

2.

发明申请
Methyl- and Trifluoromethyl-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof 审中-公开

公开(公告)号：US20180170928A1

公开(公告)日：2018-06-21

申请号：US15889296

申请日：2018-02-06

申请人： Pfizer Inc.

发明人： MARK EDWARD SCHNUTE , ANDREW CHRISTOPHER FLICK , PETER JONES , NEELU KAILA , SCOT RICHARD MENTE , JOHN DAVID TRZUPEK , MICHAEL L. VAZQUEZ , GORAN MATTIAS WENNERSTAL , LI XING , EDOUARD ZAMARATSKI , LIYING ZHANG

IPC分类号： C07D471/04 , C07D401/14

CPC分类号： C07D471/04 , C07D401/14

摘要： The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.

3.

发明申请
Methyl- and Trifluoromethyl-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof 审中-公开

公开(公告)号：US20170233390A1

公开(公告)日：2017-08-17

申请号：US15581310

申请日：2017-04-28

申请人： Pfizer Inc.

发明人： MARK EDWARD SCHNUTE , ANDREW CHRISTOPHER FLICK , PETER JONES , NEELU KAILA , SCOT RICHARD MENTE , JOHN DAVID TRZUPEK , MICHAEL L. VAZQUEZ , GÖRAN MATTIAS WENNERSTÅL , LI XING , EDOUARD ZAMARATSKI , LIYING ZHANG

IPC分类号： C07D471/04

CPC分类号： C07D471/04 , C07D401/14

摘要： The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.