Described herein are embodiments of a system and a device for performing remote ischemic conditioning that may be configured to treat a subject in accordance with particular usage restrictions and/or a particular treatment protocol. More particularly, in some embodiments a RIC device may include at least two parts, an inflatable cuff to fit around a limb of a subject and a controller that operates the inflatable cuff to inflate and deflate and thus alternate between ischemia and reperfusion of the limb in accordance with a treatment protocol. The inflatable cuff may include a computer-readable storage and that storage may include usage restrictions and/or configuration settings for the controller, to configure the controller to operate the inflatable cuff in accordance with the usage restrictions and to perform a particular treatment protocol when operating the inflatable cuff.