- 专利标题: ANTI-LAMININ4 ANTIBODIES SPECIFIC FOR LG4-5
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申请号: US15918937申请日: 2018-03-12
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公开(公告)号: US20180208646A1公开(公告)日: 2018-07-26
- 发明人: Stephen Jed Tam , Yue Liu , Robin Barbour , Theodore Yednock , Kenneth Flanagan
- 申请人: PROTHENA BIOSCIENCES LIMITED
- 主分类号: C07K16/18
- IPC分类号: C07K16/18 ; G01N33/574 ; A61K47/68 ; A61K39/00
摘要:
The invention provides antibodies that specifically bind to the LG4-5 modules of the G domain of laminin α4. The antibodies can preferentially stain cancer or tumor cells or tissue. The antibodies can be used for detecting cancer, evaluating the efficacy of a cancer therapy, treating cancer, and treating obesity or obesity-related diseases, among other applications.
公开/授权文献
- US10889636B2 Anti-Laminin4 antibodies specific for LG4-5 公开/授权日:2021-01-12
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