Invention Application
- Patent Title: DEVICE AND METHOD FOR DETECTING TARGET MOLECULES
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Application No.: US15552021Application Date: 2016-02-24
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Publication No.: US20180216181A1Publication Date: 2018-08-02
- Inventor: Jackie Y. Ying , Somenath Roy , Jun Hui Soh
- Applicant: Agency for Science, Technology and Research
- Priority: SG10201501398Q 20150225
- International Application: PCT/SG2016/050091 WO 20160224
- Main IPC: C12Q1/6876
- IPC: C12Q1/6876

Abstract:
The present invention relates to a microarray device for detecting a target molecule such as miRNA in a sample. The device comprises a carrier substrate such as glass, an anti-fouling polymer layer which is functionalised with N-Hydroxysuccinimide (NHS) or carboxyl-groups and a capture probe. In an embodiment, the capture probe is an oligonucleotide with a stem-loop structure. The invention further defines a method for fabricating the device, a kit for detecting the target nucleic acid molecule comprising the device and a detection probe.
Public/Granted literature
- US10544458B2 Device and method for detecting target molecules Public/Granted day:2020-01-28
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