发明申请
- 专利标题: COMPOSITIONS FOR INCREASING POLYPEPTIDE STABILITY AND ACTIVITY, AND RELATED METHODS
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申请号: US15728344申请日: 2017-10-09
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公开(公告)号: US20180245056A1公开(公告)日: 2018-08-30
- 发明人: Olev Kahre , Kadri Artma , Tiina Kahre
- 申请人: SOLIS BIODYNE OÜ
- 主分类号: C12N9/12
- IPC分类号: C12N9/12 ; C12N9/14 ; C12N9/00 ; C07K14/00 ; C12N9/96 ; C12N9/78 ; C12N9/50 ; C12N9/22
摘要:
This disclosure provides peptides, polypeptides, fusion polypeptides, compositions, and methods for enhancing or increasing the stability of a polypeptide (e.g., Taq polymerase). Such peptides, polypeptides, fusion polypeptides, or compositions include polypeptides linked to a peptide tag that enhances the stability of the polypeptide. The peptides, polypeptides, fusion polypeptides, compositions may also enhance the activity, specificity, and/or fidelity of other polypeptides in a reaction mixture. The disclosure also provides methods of using such peptides, polypeptides, fusion polypeptides, compositions.
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