- 专利标题： SUBPOPULATION OF CD8+CD45RCLOW TREGS AND USES THEREOF
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申请号： US15758139申请日： 2016-09-06
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公开(公告)号： US20180251731A1公开(公告)日： 2018-09-06
- 发明人: Carole GUILLONNEAU , Ignacio ANEGON , Séverine BEZIE
- 申请人： INSERM (INSTITUTE NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ DE NANTES , CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
- 优先权： EP15306366.4 20150907
- 国际申请： PCT/EP2016/070991 WO 20160906
- 主分类号： C12N5/0783
- IPC分类号： C12N5/0783 ; G01N33/50
摘要：
Disclosed is a new subpopulation of CD8+CD45RClow Tregs, namely IFNγ+IL-10+IL-34+ secreting population of CD8+CD45RClow Treg cells, methods for their isolation and expansion and their use as drug, more particularly for immunotherapy as well as biomarker