A system comprises a deployment catheter defining at least one lumen therethrough and a hood having a low profile delivery configuration and an expanded deployed configuration defining an open area of the hood. The system further comprises a laser generator sized and shaped to be passed through the lumen of the deployment catheter. The laser generator is configured to generate a pattern on tissue surface that is distal to the hood. The system further comprises a visualization element disposed within or adjacent to the open area of the hood for visualizing the tissue surface.