- 专利标题: NOVEL TETRAHYDRONAPHTHYL UREA DERIVATIVE
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申请号: US16138369申请日: 2018-09-21
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公开(公告)号: US20190023657A1公开(公告)日: 2019-01-24
- 发明人: Fumihiko SAITOH , Hiroshi NAGASUE
- 申请人: MOCHIDA PHARMACEUTICAL CO., LTD.
- 申请人地址: JP Tokyo
- 专利权人: MOCHIDA PHARMACEUTICAL CO., LTD.
- 当前专利权人: MOCHIDA PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: JP Tokyo
- 优先权: JP2017-088933 20170427; JP2017-177596 20170915
- 主分类号: C07D213/75
- IPC分类号: C07D213/75 ; A61K45/06 ; A61K31/4418 ; C07D401/04 ; A61K31/506 ; A61K31/4439 ; A61K31/444 ; C07D213/84 ; C07D405/04 ; A61K31/4433 ; C07D405/14 ; C07D213/81 ; C07D413/12 ; C07D417/04
摘要:
The present invention aims to provide a compound having a TrkA inhibitory action, a pharmaceutically acceptable salt thereof, or a solvate thereof, a pharmaceutical composition containing the same as an active ingredient, and a preventive and/or therapeutic agent for medicinal use, in particular for a disease in which TrkA in involved (pain, cancers, inflammation/inflammatory diseases, allergic diseases, skin diseases, neurodegenerative diseases, infectious diseases, Sjogren's syndrome, endometriosis, renal diseases, osteoporosis, and the like). Specifically, the present invention provides a compound or an optical isomer thereof, a pharmaceutically acceptable salt thereof, a solvate thereof, or the like, the compound represented by formula (I):
公开/授权文献
- US10399945B2 Tetrahydronaphthyl urea derivative 公开/授权日:2019-09-03
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