- 专利标题: 2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS
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申请号: US15756867申请日: 2016-12-07
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公开(公告)号: US20190062326A1公开(公告)日: 2019-02-28
- 发明人: Martina DELBECK , Michael HAHN , Thomas MÜLLER , Heinrich MEIER , Klemens LUSTIG , Johanna MOSIG , Luisella TOSCHI , Udo ALBUS , Doris GEHRING , Björn ROSENSTEIN
- 申请人: BAYER PHARMA AKTIENGESELLSCHAFT
- 申请人地址: DE Berlin
- 专利权人: BAYER PHARMA AKTIENGESELLSCHAFT
- 当前专利权人: BAYER PHARMA AKTIENGESELLSCHAFT
- 当前专利权人地址: DE Berlin
- 优先权: EP15199270.8 20151210; EP16196836.7 20161102
- 国际申请: PCT/EP2016/079973 WO 20161207
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/496 ; A61K45/06 ; A61P11/16
摘要:
The present application relates to novel 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring.
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