Invention Application
- Patent Title: 5-ARYL-1H-PYRROLE-3-CARBONITRILE AND A PHARMACEUTICAL PRODUCT USING THE SAME
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Application No.: US16200178Application Date: 2018-11-26
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Publication No.: US20190127324A1Publication Date: 2019-05-02
- Inventor: Tomomi Ikemoto , Hideya Mizufune , Toshiaki Nagata , Misayo Sera , Naohiro Fukuda , Takeshi Yamasaki
- Applicant: Takeda Pharmaceutical Company Limited
- Priority: JP2009-042975 20090225
- Main IPC: C07D207/337
- IPC: C07D207/337 ; C07D207/333 ; C07D207/34 ; C07D207/48 ; C07D401/12 ; C07D207/30 ; C07D207/36

Abstract:
The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.
Public/Granted literature
- US10538489B2 5-aryl-1H-pyrrole-3-carbonitrile and a pharmaceutical product using the same Public/Granted day:2020-01-21
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