- 专利标题： SOLUTION COMPRISING THE CHLORIDE HYDROCHLORIDE SALT OF 4-(5-(2-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-N,2-DIMETHYLPROPANAMIDO)-4-(o-TOLYL)PYRIDIN-2-YL)-1-METHYL-1-((PHOSPHONOOXY)METHYL)PIPERAZIN-1-IUM (FOSNETUPITANT) AND PALONOSETRON HYDROCHLORIDE IN COMBINATION WITH DEXAMETHASONE AS A NEUROKININ RECEPTOR MODULATOR
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申请号： US16228835申请日： 2018-12-21
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公开(公告)号： US20190177296A1公开(公告)日： 2019-06-13
- 发明人: Luca Fadini , Peter Manini , Claudio Pietra , Claudio Giuliano , Emanuela Lovati , Roberta Cannella , Alessio Venturini , Valentino J. Stella
- 申请人： HELSINN HEALTHCARE SA
- 主分类号： C07D401/04
- IPC分类号： C07D401/04 ; A61K9/00 ; A61K31/496 ; A61K31/573 ; A61K31/473 ; A61P1/08 ; A61P13/10 ; A61P25/24 ; A61P25/22
摘要：
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor. The compounds have the general formula (I):
公开/授权文献
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