- 专利标题： COMPOSITIONS AND METHODS FOR EVALUATING AND MODULATING IMMUNE RESPONSES
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申请号： US16331410申请日： 2017-09-07
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公开(公告)号： US20190262399A1公开(公告)日： 2019-08-29
- 发明人: Chao Wang , Meromit Singer , Aviv Regev , Vijay K. Kuchroo
- 申请人： The Broad Institute, Inc. , Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc.
- 国际申请： PCT/US2017/050469 WO 20170907
- 主分类号： A61K35/17
- IPC分类号： A61K35/17 ; G01N33/50 ; A61P35/00 ; G16H50/70 ; G16H50/30 ; G16B25/10 ; C12Q1/6809 ; C12Q1/6811 ; C12Q1/6851 ; C12Q1/6853
摘要：
The present invention provides markers, marker signatures and molecular targets that correlate with dysfunction or activation of immune cells. The present markers, marker signatures and molecular targets provide for new ways to evaluate and modulate immune responses. Therapeutic methods are also provided to treat a patient in need thereof who would benefit from a modulated immune response.
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