Embodiments of the disclosure provide methods and apparatus for positioning in a wireless network. One embodiment provides a method, performed by a target device, for enabling detection of a narrowband positioning reference signal, NPRS, location in a radio frame. The method includes: obtaining, from a location server, assistance data related to a neighbour cell in a reference and neighbour cell list. The assistance data includes timing offset information for the neighbour cell; determining a time of a NPRS subframe for the neighbour cell and/or NPRS sequence based on the timing offset information; measuring a positioning reference signal (PRS) based on the determined time; and reporting the measured PRS to the location server.