Invention Application
- Patent Title: Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
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Application No.: US16275938Application Date: 2019-02-14
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Publication No.: US20190290645A1Publication Date: 2019-09-26
- Inventor: Wilhelm Amberg , Frauke Pohlki , Udo Lange , Ying Wang , Jason Brewer , Anil Vasudevan , Yanbin Lao , Charles Hutchins , Hongyu Zhao , Huan-Qiu Li
- Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
- Main IPC: A61K31/501
- IPC: A61K31/501 ; A61K31/4433 ; A61K31/4192 ; A61K31/4178 ; C07D405/04 ; A61K31/397 ; C07D311/58 ; C07D405/14 ; A61K31/4155

Abstract:
The present invention relates to aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives of the formula (I) or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, and the use of such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives for therapeutic purposes. The aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives are GlyT1 inhibitors.
Information query
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