- 专利标题: METHOD FOR INCREASING THROUGHPUT OF SINGLE MOLECULE SEQUENCING BY CONCATENATING SHORT DNA FRAGMENTS
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申请号: US16443674申请日: 2019-06-17
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公开(公告)号: US20200010875A1公开(公告)日: 2020-01-09
- 发明人: Janine Mok , Ulrich Schlecht , Austin So
- 申请人: Roche Sequencing Solutions, Inc.
- 主分类号: C12Q1/6811
- IPC分类号: C12Q1/6811 ; C12Q1/6806 ; C12Q1/686 ; C12Q1/6876 ; C12Q1/6855 ; C40B40/06 ; C40B80/00 ; C40B50/08
摘要:
The invention comprises a novel method and compositions for sequencing library preparation, which increases the throughput of single-molecule sequencing (SMS) platforms by generating long concatenated templates from pools of short DNA molecules.