- 专利标题： POLOXAMER COMPOSITION FREE OF LONG CIRCULATING MATERIAL AND METHODS FOR PRODUCTION AND USES THEREOF
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申请号： US16660915申请日： 2019-10-23
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公开(公告)号： US20200055983A1公开(公告)日： 2020-02-20
- 发明人: R. Martin Emanuele , Mannarsamy BALASUBRAMANIAN , Stewart V. SMITH
- 申请人： LifeRaft Biosciences, Inc.
- 申请人地址： US SC Mt. Pleasant
- 专利权人： LifeRaft Biosciences, Inc.
- 当前专利权人： LifeRaft Biosciences, Inc.
- 当前专利权人地址： US SC Mt. Pleasant
- 主分类号： C08G65/30
- IPC分类号： C08G65/30 ; A61K35/19 ; A61K35/18 ; C08G65/08 ; A61K35/14 ; A61K31/77 ; A61K9/00
摘要：
Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.