- 专利标题: STABLE INTRANASAL FORMULATIONS OF CARBETOCIN
-
申请号: US16576940申请日: 2019-09-20
-
公开(公告)号: US20200093884A1公开(公告)日: 2020-03-26
- 发明人: Mark C. MANNING , Ryan E. Holcomb , Derrick S. Katayama , Christopher Bryant
- 申请人: Mark C. MANNING , Ryan E. Holcomb , Derrick S. Katayama , Christopher Bryant
- 主分类号: A61K38/095
- IPC分类号: A61K38/095 ; A61K47/38 ; A61K9/08 ; A61K9/00 ; A61K47/55
摘要:
The application describes stable aqueous compositions comprising relatively high concentrations of carbetocin and a solubilizer and/or surface active agent. The disclosed carbetocin compositions are effective in the treatment of a neurodevelopmental disorder, such as Präder-Willi syndrome. Additionally, the disclosed carbetocin compositions show improved stability at room temperature and/or under accelerated conditions of stress.