Invention Application
- Patent Title: Advanced Processing of Absorbable Poly(p-dioxanone) Containing High Level of p-Dioxanone Monomer
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Application No.: US16202454Application Date: 2018-11-28
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Publication No.: US20200165380A1Publication Date: 2020-05-28
- Inventor: Sasa Andjelic , Brian M. Kelly , Marc Wisnudel
- Applicant: Ethicon, Inc.
- Main IPC: C08G63/66
- IPC: C08G63/66 ; C08G63/78 ; C08G63/85 ; C08K5/18 ; C08J3/12

Abstract:
The present invention is directed methods of making absorbable poly(p-dioxanone) pellets by melt polymerization of p-dioxanone conducted in a single reactor with a temperature regulator by charging a melt reactor with a mixture of p-dioxanone (PDO) monomer, initiator, catalyst, and optionally a dye; melt polymerizing the mixture in the melt reactor with sufficient agitation of the mixture to allow complete mixing of the monomer and for sufficient time to form a PDO polymer product having an unreacted PDO monomer content of at least 65 mole percent; placing the PDO polymer product under a vacuum to remove at least portion of unreacted PDO; discharging the PDO polymer product from the melt reactor directly into an in-line, underwater pelletizer to produce undried PDO pellets, collecting the undried PDO pellets, and storing the collected PDO pellets in the freezer or a vacuum chamber prior to drying.
Public/Granted literature
- US11028222B2 Advanced processing of absorbable poly(p-dioxanone) containing high level of p-dioxanone monomer Public/Granted day:2021-06-08
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