Disclosed are a method for selecting a transmission resource for a transport block (TB) by a user equipment (UE) in a wireless communication system and an apparatus therefor according to various embodiments. Specifically, disclosed are a method for selecting a transmission resource for a transport block (TB) by a user equipment (UE) in a wireless communication system and an apparatus therefor, the method comprising the steps of: arbitrarily selecting one frequency section from among multiple frequency sections divided from a system band at predetermined frequency intervals, and determining a first transmission resource for transmitting the transport block (TB) on the basis of the arbitrarily-selected frequency section; and transmitting the transport block, using the determined first transmission resource, wherein a guard band, which is a frequency band which is not selected as the first transmission resource, is formed in the arbitrarily-selected frequency section.