- 专利标题： PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS
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申请号： US16858319申请日： 2020-04-24
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公开(公告)号： US20200255375A1公开(公告)日： 2020-08-13
- 发明人: Pravin Sudhakar Shirude , Vishweshwaraiah Baligar , Balaji Seshadri , Amit Kumar Chattopadhyay , Nicholas R. Wurtz , Ellen K. Kick
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 主分类号： C07D207/14
- IPC分类号： C07D207/14 ; C07D403/12 ; A61P9/04 ; C07D409/12 ; C07D413/10 ; A61P9/10 ; C07D401/12 ; C07D401/10 ; C07D403/10 ; C07D413/14 ; C07D417/10 ; C07F9/6558 ; A61P9/00 ; C07F9/572 ; C07D405/10
摘要：
The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
公开/授权文献
- US11117861B2 Phenylpyrrolidinone formyl peptide 2 receptor agonists 公开/授权日：2021-09-14