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公开(公告)号:US11008301B2
公开(公告)日:2021-05-18
申请号:US16619960
申请日:2018-06-08
发明人: Pravin Sudhakar Shirude , Amit Kumar Chattopadhyay , Chandrasekhar Rachamreddy , Nicholas R. Wurtz , Ellen K. Kick
IPC分类号: C07D401/10 , A61P9/00 , C07D401/14 , C07D413/14 , C07D491/107 , C07D498/08
摘要: The disclosure relates to compounds of formula (I), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, and related diseases.
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公开(公告)号:US20190270704A1
公开(公告)日:2019-09-05
申请号:US16291209
申请日:2019-03-04
发明人: Pravin Sudhakar Shirude , Vishweshwaraiah Baligar , Balaji Seshadri , Amit Kumar Chattopadhyay , Nicholas R. Wurtz , Ellen K. Kick
IPC分类号: C07D207/14 , C07D403/10 , C07D401/10 , C07D401/12 , C07D403/12 , C07D413/10 , C07D409/12 , A61P9/04 , A61P9/10
摘要: The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
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公开(公告)号:US20210371378A1
公开(公告)日:2021-12-02
申请号:US17400421
申请日:2021-08-12
发明人: Pravin Sudhakar Shirude , Vishweshwaraiah Baligar , Balaji Seshadri , Amit Kumar Chattopadhyay , Nicholas R. Wurtz , Ellen K. Kick
IPC分类号: C07D207/14 , C07D403/10 , C07D401/10 , C07D401/12 , A61P9/10 , C07D413/10 , C07D409/12 , A61P9/04 , C07D403/12 , C07F9/6558 , C07D405/10 , C07F9/572 , A61P9/00 , C07D417/10 , C07D413/14 , A61K31/4015 , A61K31/4439 , A61K31/497 , A61K31/675
摘要: The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
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公开(公告)号:US11117861B2
公开(公告)日:2021-09-14
申请号:US16858319
申请日:2020-04-24
发明人: Pravin Sudhakar Shirude , Vishweshwaraiah Baligar , Balaji Seshadri , Amit Kumar Chattopadhyay , Nicholas R. Wurtz , Ellen K. Kick
IPC分类号: A61K31/4015 , A61K31/4439 , A61K31/497 , A61K31/675 , C07D207/14 , C07D403/10 , C07D401/10 , C07D401/12 , A61P9/10 , C07D413/10 , C07D409/12 , A61P9/04 , C07D403/12 , C07F9/6558 , C07D405/10 , C07F9/572 , A61P9/00 , C07D417/10 , C07D413/14
摘要: The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
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公开(公告)号:US20200255375A1
公开(公告)日:2020-08-13
申请号:US16858319
申请日:2020-04-24
发明人: Pravin Sudhakar Shirude , Vishweshwaraiah Baligar , Balaji Seshadri , Amit Kumar Chattopadhyay , Nicholas R. Wurtz , Ellen K. Kick
IPC分类号: C07D207/14 , C07D403/12 , A61P9/04 , C07D409/12 , C07D413/10 , A61P9/10 , C07D401/12 , C07D401/10 , C07D403/10 , C07D413/14 , C07D417/10 , C07F9/6558 , A61P9/00 , C07F9/572 , C07D405/10
摘要: The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
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公开(公告)号:US20200207735A1
公开(公告)日:2020-07-02
申请号:US16619960
申请日:2018-06-08
发明人: Pravin Sudhakar Shirude , Amit Kumar Chattopadhyay , Chandrasekhar Rachamreddy , Nicholas R. Wurtz , Ellen K. Kick
IPC分类号: C07D401/10 , C07D498/08 , C07D401/14 , C07D413/14 , C07D491/107 , A61P9/00
摘要: The disclosure relates to compounds of formula (I), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, and related diseases.
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公开(公告)号:US20220298186A1
公开(公告)日:2022-09-22
申请号:US17616748
申请日:2020-06-16
IPC分类号: C07F9/6558 , C07F9/59
摘要: The disclosure relates to compounds of Formula (I), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
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8.
公开(公告)号:US11124494B2
公开(公告)日:2021-09-21
申请号:US16619965
申请日:2018-06-08
IPC分类号: C07D401/12 , C07D211/56 , C07D413/10
摘要: The disclosure relates to compounds of formula (I), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, and related diseases.
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公开(公告)号:US10676431B2
公开(公告)日:2020-06-09
申请号:US16291209
申请日:2019-03-04
发明人: Pravin Sudhakar Shirude , Vishweshwaraiah Baligar , Balaji Seshadri , Amit Kumar Chattopadhyay , Nicholas R. Wurtz , Ellen K. Kick
IPC分类号: C07D207/14 , C07D403/10 , C07D401/10 , C07D401/12 , C07D413/10 , C07D409/12 , A61P9/04 , C07D403/12 , C07F9/6558 , C07D405/10 , C07F9/572 , A61P9/00 , C07D417/10 , C07D413/14 , A61P9/10
摘要: The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
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