发明申请
- 专利标题： ANTIBODIES BINDING TO CD3
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申请号： US16721254申请日： 2019-12-19
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公开(公告)号： US20200270347A1公开(公告)日： 2020-08-27
- 发明人: Anne FREIMOSER-GRUNDSCHOBER , Thomas HOFER , Ralf HOSSE , Ekkehard MOESSNER , Valeria G. NICOLINI , Pablo UMAÑA , lnja WALDHAUER , Wolfgang Richter , Alexander KNAUPP , Halina TROCHANOWSKA
- 申请人： Hoffmann-La Roche Inc.
- 申请人地址： US NJ Little Falls
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Little Falls
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@11a1f9af
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/30 ; A61P35/00
摘要：
The present invention generally relates to antibodies that bind to CD3, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
公开/授权文献
- US11672858B2 Bispecific antibody molecules binding to CD3 and TYRP-1 公开/授权日：2023-06-13
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