Invention Application
- Patent Title: SUBSTITUTED CYCLYL-ACETIC ACID DERIVATIVES FOR THE TREATMENT OF METABOLIC DISORDERS
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Application No.: US16497141Application Date: 2018-03-29
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Publication No.: US20200377509A1Publication Date: 2020-12-03
- Inventor: Seiji MIWATASHI , Yasufumi MIYAMOTO , Koji WATANABE , Yayoi NAKAYAMA , Yuko HITOMI , Jumpei AIDA , Nobuyuki TAKAKURA , Hideki FURUKAWA , Naoyoshi NOGUCHI , Yasuhiro HIRATA , Shizuo KASAl , Toshitake KOBAYASHI , Tsuyoshi MAEKAWA , Satoshi SASAKI , Shigemitsu MATSUMOTO
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED , SCOHIA PHARMA, INC
- Applicant Address: JP Osaka JP Kanagawa
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED,SCOHIA PHARMA, INC
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED,SCOHIA PHARMA, INC
- Current Assignee Address: JP Osaka JP Kanagawa
- Priority: JP2017-072813 20170331
- International Application: PCT/JP2018/014501 WO 20180329
- Main IPC: C07D491/052
- IPC: C07D491/052 ; C07D401/12 ; C07D401/14 ; C07D211/22
Abstract:
Provided is a novel aromatic ring compound which may have a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof may have a GPR40 agonist activity and a GLP-1 secretagogue action, may be useful for the prophylaxis or treatment of cancer, obesity, diabetes, hypertension, hyperlipidemia, cardiac failure, diabetic complications, metabolic syndrome, sarcopenia and the like, and may afford superior efficacy.
Public/Granted literature
- US10968231B2 Substituted cyclyl-acetic acid derivatives for the treatment of metabolic disorders Public/Granted day:2021-04-06
Information query
