- 专利标题： PHARMACEUTICAL COMPOSITIONS CONTAINING POLYROTAXANES
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申请号： US17041215申请日： 2019-03-26
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公开(公告)号： US20210008220A1公开(公告)日： 2021-01-14
- 发明人: May XIONG , Zhi LIU
- 申请人： UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
- 申请人地址： US GA Athens
- 专利权人： UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
- 当前专利权人： UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
- 当前专利权人地址： US GA Athens
- 国际申请： PCT/US2019/024009 WO 20190326
- 主分类号： A61K47/61
- IPC分类号： A61K47/61 ; C08G83/00 ; C08B37/16 ; A61K31/164 ; A61K31/4196 ; A61K31/4412
摘要：
Disclosed herein are a polyrotaxane conjugated metal chelators and selectively cleavable linkers. The compositions have prolonged plasma residence time, and upon contact with the appropriate chemical environment, are cleaved and then renally and fecally cleared.
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