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公开(公告)号:US20210008220A1
公开(公告)日:2021-01-14
申请号:US17041215
申请日:2019-03-26
IPC分类号: A61K47/61 , C08G83/00 , C08B37/16 , A61K31/164 , A61K31/4196 , A61K31/4412
摘要: Disclosed herein are a polyrotaxane conjugated metal chelators and selectively cleavable linkers. The compositions have prolonged plasma residence time, and upon contact with the appropriate chemical environment, are cleaved and then renally and fecally cleared.