Methods, apparatus, systems and articles of manufacture (e.g., physical storage media) to protect against misuse of software defined silicon products are disclosed. Example semiconductor devices disclosed herein include circuitry configurable to provide one or more features. Disclosed example semiconductor devices also include a license processor determine whether first identification information associated with a license received via a network from an enterprise system corresponds to second identification information associated with at least one of the semiconductor device or a customer, and configure the circuitry to activate a first one of the one or more features specified in the license in response to the first identification information corresponding to the second identification information.