- 专利标题： FIBROBLAST BINDING AGENTS AND USE THEREOF
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申请号： US16967288申请日： 2019-02-05
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公开(公告)号： US20210023167A1公开(公告)日： 2021-01-28
- 发明人: Nikolai KLEY , Jan TAVERNIER , Anje CAUWELS
- 申请人： Orionis Biosciences, Inc. , VIB VZW , Universiteit Gent
- 申请人地址： US MA Waltham; BE Gent; BE Gent
- 专利权人： Orionis Biosciences, Inc.,VIB VZW,Universiteit Gent
- 当前专利权人： Orionis Biosciences, Inc.,VIB VZW,Universiteit Gent
- 当前专利权人地址： US MA Waltham; BE Gent; BE Gent
- 国际申请： PCT/US19/16629 WO 20190205
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C07K14/555 ; A61K31/704
摘要：
The present invention relates, in part, to agents that bind fibroblast activation protein (FAP) and their use as diagnostic and therapeutic agents. The present invention further relates to pharmaceutical compositions comprising the FAP binding agents and their use in the treatment of various diseases.