A method of manufacturing a sock including the steps of knitting the sock on a knitting machine with a first yarn, such as a cotton or polyester yarn, and a second yarn that is a silicone yarn wrapped with poly vinyl acetate (PVA) yarn. The PVA yarn substantially fully encapsulates the silicone yarn, with one PVA yarn being wrapped around the silicone yarn in a “S” twist pattern and the second PVA yarn being wrapped around the silicone yarn in a “Z” twist pattern. The sock is bathed in hot water after being knitted such that the PVA yarn dissolves and exposes the silicone yarn. The second yarn is knitted in the sock to form defined areas or patterns of silicone yarns within the sock, such as in the toe and heel areas. The resulting sock provides grip and slip-resistance properties on both the inside and outside of the sock.