The present invention provides a dynamic contact heat transfer simulation device for rolling heavy-load deformation zone. The device includes a control system, a data acquisition system, a pressure-adjustable fixed cold end, a rotating chuck, a temperature-adjustable heat-conducting rod and an speed-adjustable rotation hot end; the device utilizes the rotating chuck and the speed-adjustable rotating hot end to adjust the rotation speed in real time according to the actual rolling conditions, simulate the working conditions of the actual rolling heavy-load deformation zone, and accurately obtain the dynamic heat transfer coefficient of the rotating contact interface under variable load pressure conditions.