- 专利标题： ACETYLATED PRODRUGS FOR DELIVERY ACROSS THE BLOOD-BRAIN BARRIER
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申请号： US17049230申请日： 2019-04-22
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公开(公告)号： US20210238124A1公开(公告)日： 2021-08-05
- 发明人: David R. ELMALEH , Timothy M. SHOUP
- 申请人： THE GENERAL HOSPITAL CORPORATION
- 申请人地址： US MA Boston
- 专利权人： THE GENERAL HOSPITAL CORPORATION
- 当前专利权人： THE GENERAL HOSPITAL CORPORATION
- 当前专利权人地址： US MA Boston
- 国际申请： PCT/US19/28515 WO 20190422
- 主分类号： C07C233/18
- IPC分类号： C07C233/18 ; C07C219/28 ; C07C217/60 ; A61K51/04 ; A61K51/12
摘要：
The present disclosure relates to pharmaceutical compositions including a compound derived from a parent compound having a hydroxyl or amino moiety, wherein the hydroxyl in the parent compound is presented as an ester in the compound or the amino in the parent compound is presented as an amide in the compound, and their use to prevent or treat neurological disease.
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