专利检索 ap:("THE GENERAL HOSPITAL CORPORATION") AND inv:"Timothy M. SHOUP" 第 1 页

1.

发明申请
ACETYLATED PRODRUGS FOR DELIVERY ACROSS THE BLOOD-BRAIN BARRIER 有权

公开(公告)号：US20210238124A1

公开(公告)日：2021-08-05

申请号：US17049230

申请日：2019-04-22

申请人： THE GENERAL HOSPITAL CORPORATION

发明人： David R. ELMALEH , Timothy M. SHOUP

IPC分类号： C07C233/18 , C07C219/28 , C07C217/60 , A61K51/04 , A61K51/12

摘要： The present disclosure relates to pharmaceutical compositions including a compound derived from a parent compound having a hydroxyl or amino moiety, wherein the hydroxyl in the parent compound is presented as an ester in the compound or the amino in the parent compound is presented as an amide in the compound, and their use to prevent or treat neurological disease.