- 专利标题： Pharmaceutical Composition Comprising Compound Capable of Penetrating Blood-Brain Barrier as Effective Ingredient for Preventing or Treating Brain Cancer
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申请号： US16488706申请日： 2018-02-23
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公开(公告)号： US20210267997A1公开(公告)日： 2021-09-02
- 发明人: Hwan Geun Choi , Jong Bae Park , Eunhwa Ko , Jung Beom Son , Nam Doo Kim , Seung Hoon Lee , Do-Hyun Nam
- 申请人： DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION , NATIONAL CANCER CENTER , SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
- 申请人地址： KR Daegu; KR Gyeonggi-do; KR Seoul
- 专利权人： DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION,NATIONAL CANCER CENTER,SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
- 当前专利权人： DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION,NATIONAL CANCER CENTER,SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
- 当前专利权人地址： KR Daegu; KR Gyeonggi-do; KR Seoul
- 优先权： KR10-2017-0024812 20170224
- 国际申请： PCT/KR2018/002241 WO 20180223
- 主分类号： A61K31/5513
- IPC分类号： A61K31/5513 ; A61K31/506 ; A61K31/437 ; A61K31/5377 ; A61K31/4365 ; A61K31/415 ; C07K16/22 ; A61P35/04
摘要：
Disclosed is a pharmaceutical composition for the prevention or treatment of brain cancer, containing a compound capable of penetrating the blood-brain barrier as an active ingredient, the pharmaceutical composition for the prevention or treatment of brain cancer is capable of efficiently penetrating the blood-brain barrier of the brain to thereby effectively inhibit LRRK2 protein expression, and is thus useful in the prevention or treatment of brain cancer.