- 专利标题： FUSED TRICYCLIC KRAS INHIBITORS
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申请号： US17231547申请日： 2021-04-15
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公开(公告)号： US20210355121A1公开(公告)日： 2021-11-18
- 发明人: Wenyu ZHU , Xiaozhao WANG , Artem SHVARTSBART , Chao Qi , Rocco Policarpo , Wenqing Yao
- 申请人： Incyte Corporation
- 申请人地址： US DE Wilmington
- 专利权人： Incyte Corporation
- 当前专利权人： Incyte Corporation
- 当前专利权人地址： US DE Wilmington
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D519/00 ; A61P35/00 ; A61K9/00
摘要：
Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.
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