- 专利标题: BISPECIFIC ANTIGEN BINDING MOLECULES COMPRISING LIPOCALIN MUTEINS
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申请号: US17498515申请日: 2021-10-11
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公开(公告)号: US20220025069A1公开(公告)日: 2022-01-27
- 发明人: Christina CLAUS , Claudia FERRARA KOLLER , Christian KLEIN , Pablo UMAÑA
- 申请人: Hoffmann-La Roche Inc.
- 申请人地址: US NJ Little Falls
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Little Falls
- 优先权: EP19169022.1 20190412
- 主分类号: C07K16/40
- IPC分类号: C07K16/40 ; C07K14/475 ; C07K16/46 ; C07K16/32
摘要:
The invention relates to bispecific antigen binding molecule capable of bivalent binding to 4-1BB and monovalent binding to a target cell antigen comprising two lipocalin muteins capable of specific binding to 4-1BB and their use in the treatment of cancer or infectious diseases.
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