- 专利标题: METHODS OF MAKING ANTIBODIES
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申请号: US17454015申请日: 2021-11-08
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公开(公告)号: US20220056134A1公开(公告)日: 2022-02-24
- 发明人: Kamal Kishore JOSHI , Paul J. Carter , Yiyuan Yin
- 申请人: Genentech, Inc.
- 申请人地址: US CA South San Francisco
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; C12N5/10
摘要:
Provided are, inter alia, methods of improving pairing of a heavy chain and a light chain of an antibody (such as a bispecific antibody). Also provided are antibodies (e.g., bispecific antibodies) generated using such methods, libraries, and methods of screening such libraries.
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