- 专利标题： DELIVERY OF BIOMOLECULES TO IMMUNE CELLS
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申请号： US17394125申请日： 2021-08-04
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公开(公告)号： US20220064584A1公开(公告)日： 2022-03-03
- 发明人: Armon R. Sharei , Shirley Mao , George Hartoularos , Sophia Liu , Megan Heimann , Pamela Basto , Gregory Szeto , Siddharth Jhunjhunwala , Darrell J. Irvine , Robert S. Langer , Klavs F. Jensen , Ulrich H. Von Andrian
- 申请人： Massachusetts Institute of Technology , President and Fellows of Harvard College
- 申请人地址： US MA Cambridge; US MA Cambridge
- 专利权人： Massachusetts Institute of Technology,President and Fellows of Harvard College
- 当前专利权人： Massachusetts Institute of Technology,President and Fellows of Harvard College
- 当前专利权人地址： US MA Cambridge; US MA Cambridge
- 主分类号： C12M1/42
- IPC分类号： C12M1/42 ; C12N15/87 ; A61K39/00 ; A61K45/06 ; A61K49/00 ; C12M3/06 ; C12N5/0781 ; C12N5/0783 ; C12N5/0784 ; G01N33/50
摘要：
A method and device for preferentially delivering a compound such as an antigen to the cytosol of an immune cell. The method comprises passing a cell suspension comprising the target immune cell through a microfluidic device and contacting the suspension with the compound(s) or payload to be delivered.
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