- 专利标题： INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION
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申请号： US17422642申请日： 2020-01-10
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公开(公告)号： US20220089585A1公开(公告)日： 2022-03-24
- 发明人: Dane James Clausen , Joseph A. Kozlowski , Jian Liu , Scott E. Wolkenberg , Wengsheng Yu
- 申请人： Dane James CLAUSEN , Joseph A. KOZLOWSKI , Jian LIU , Scott E. WOLKENBERG , Wensheng YU , Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway; US NJ Princeton; US NJ Kenilworth; US PA West Point; US NJ Kenilworth; US NJ Rahway
- 专利权人： Dane James CLAUSEN,Joseph A. KOZLOWSKI,Jian LIU,Scott E. WOLKENBERG,Wensheng YU,Merck Sharp & Dohme Corp.
- 当前专利权人： Dane James CLAUSEN,Joseph A. KOZLOWSKI,Jian LIU,Scott E. WOLKENBERG,Wensheng YU,Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway; US NJ Princeton; US NJ Kenilworth; US PA West Point; US NJ Kenilworth; US NJ Rahway
- 国际申请： PCT/US20/13080 WO 20200110
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D413/12 ; A61K45/06 ; A61K31/422 ; A61K31/4709 ; C07D417/14 ; A61P31/18
摘要：
The present invention relates to Compounds of Formula I and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, R3, R4, X and A are as defined herein. The present invention also relates to compositions comprising at least one compound of Formula I, and methods of using the compounds of Formula I for treating or preventing HIV infection in a subject.
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