- 专利标题： EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF
-
申请号： US17551592申请日： 2021-12-15
-
公开(公告)号： US20220106350A1公开(公告)日： 2022-04-07
- 发明人: Marie Eugenie Migaud , Philip Redpath , Kerri Crossey , Richard Cunningham , Aron Erickson , Richard Nygaard , Amanda Storjohann
- 申请人： The Queen's University of Belfast , ChromaDex Inc.
- 申请人地址： GB Belfast; US CA Irvine
- 专利权人： The Queen's University of Belfast,ChromaDex Inc.
- 当前专利权人： The Queen's University of Belfast,ChromaDex Inc.
- 当前专利权人地址： GB Belfast; US CA Irvine
- 主分类号： C07H19/048
- IPC分类号： C07H19/048 ; C07D307/20 ; C07H19/20
摘要：
The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X−, Z1, Z2, n, R1, R2, R3, R4, R5, R6, R7, and R8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.
信息查询
IPC分类:
