Invention Application
- Patent Title: FERMENTATIVE GLYCEROL-FREE ETHANOL PRODUCTION
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Application No.: US17531218Application Date: 2021-11-19
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Publication No.: US20220135989A1Publication Date: 2022-05-05
- Inventor: Jacobus Thomas PRONK , Antonius Jeroen Adriaan VAN MARIS , Victor Gabriel GUADALUPE MEDINA
- Applicant: DSM IP Assets B.V.
- Applicant Address: NL Heerlen
- Assignee: DSM IP Assets B.V.
- Current Assignee: DSM IP Assets B.V.
- Current Assignee Address: NL Heerlen
- Priority: EP09166360.9 20090724
- Main IPC: C12N15/81
- IPC: C12N15/81 ; C12N1/18 ; C12N9/02 ; C12P7/10 ; C12P7/06 ; C12N9/04 ; C12N9/00

Abstract:
The present invention relates to a yeast cell, in particular a recombinant yeast cell, the cell lacking enzymatic activity needed for the NADH-dependent glycerol synthesis or the cell having a reduced enzymatic activity with respect to the NADH-dependent glycerol synthesis compared to its corresponding wild-type yeast cell, the cell comprising one or more heterologous nucleic acid sequences encoding an NAD+-dependent acetylating acetaldehyde dehydrogenase (EC 1.2.1.10) activity. The invention further relates to the use of a cell according to the invention in the preparation of ethanol.
Information query
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