Invention Application

LIQUID CHROMATOGRAPH
Abstract:
A liquid chromatograph (1) includes a liquid sending pump (14) for sending a mobile phase, a sample injector (4) that injects a sample into an analysis flow path (12) through which a mobile phase from the liquid sending pump (14) flows, a separation column (6) that is provided on the analysis flow path (12) and is to separate a sample that has been injected into the analysis flow path (12) by the sample injector (4) into components, a pressure sensor (16) for detecting a liquid sending pressure in the analysis flow path (12) located at a position farther upstream than the separation column (6), a damper capacity holder (22) that holds an internal capacity of a system through which a mobile phase from the liquid sending pump (14) flows as a damper capacity, a reference value determiner (24) configured to determine a reference value of a fluctuation range of the liquid sending pressure when a liquid sending failure of the liquid sending pump (14) occurs, using at least the damper capacity held by the damper capacity holder (22), and a liquid sending failure detector (26) that is configured to periodically acquire a liquid sending pressure detected by the pressure sensor (16), obtain a fluctuation range of the liquid sending pressure in a certain driving period of the liquid sending pump (14) and detect a liquid sending failure using the obtained fluctuation range and the reference value determined by the reference value determiner (24).
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