Invention Application
- Patent Title: LIQUID CHROMATOGRAPH
-
Application No.: US17438419Application Date: 2019-03-13
-
Publication No.: US20220146474A1Publication Date: 2022-05-12
- Inventor: Tomohiro GOMI , Daisuke KITABAYASHI
- Applicant: SHIMADZU CORPORATION
- Applicant Address: JP Kyoto
- Assignee: SHIMADZU CORPORATION
- Current Assignee: SHIMADZU CORPORATION
- Current Assignee Address: JP Kyoto
- International Application: PCT/JP2019/010420 WO 20190313
- Main IPC: G01N30/86
- IPC: G01N30/86 ; G01N30/32

Abstract:
A liquid chromatograph (1) includes a liquid sending pump (14) for sending a mobile phase, a sample injector (4) that injects a sample into an analysis flow path (12) through which a mobile phase from the liquid sending pump (14) flows, a separation column (6) that is provided on the analysis flow path (12) and is to separate a sample that has been injected into the analysis flow path (12) by the sample injector (4) into components, a pressure sensor (16) for detecting a liquid sending pressure in the analysis flow path (12) located at a position farther upstream than the separation column (6), a damper capacity holder (22) that holds an internal capacity of a system through which a mobile phase from the liquid sending pump (14) flows as a damper capacity, a reference value determiner (24) configured to determine a reference value of a fluctuation range of the liquid sending pressure when a liquid sending failure of the liquid sending pump (14) occurs, using at least the damper capacity held by the damper capacity holder (22), and a liquid sending failure detector (26) that is configured to periodically acquire a liquid sending pressure detected by the pressure sensor (16), obtain a fluctuation range of the liquid sending pressure in a certain driving period of the liquid sending pump (14) and detect a liquid sending failure using the obtained fluctuation range and the reference value determined by the reference value determiner (24).
Public/Granted literature
- US12007373B2 Liquid chromatograph Public/Granted day:2024-06-11
Information query