Invention Application
- Patent Title: COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE AGAINST CLOSTRIDIUM DIFFICILE
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Application No.: US17594107Application Date: 2020-03-30
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Publication No.: US20220160859A1Publication Date: 2022-05-26
- Inventor: Kathrin Ute Jansen , Annaliesa Sybil Anderson , Alexey Vyacheslavovitch Gribenko , Nicholas Randolph Everard Kitchin , Paul Liberator , Michael William Pride , Christopher Frederick Webber
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- International Application: PCT/IB2020/053005 WO 20200330
- Main IPC: A61K39/08
- IPC: A61K39/08 ; A61P31/04 ; C07K14/33 ; C07K16/12
Abstract:
In one aspect, the invention relates to an immunogenic composition that includes a Clostridium difficile toxoid A and/or a C. difficile toxoid B, and methods of use thereof. In another aspect, the invention relates to a method for eliciting an immune response in a human against a C. difficile infection. The method includes administering to the human an effective dose of a composition, which includes a C. difficile toxoid, wherein the composition is administered at least two times, and wherein the immune response against C. difficile toxin A and/or toxin B is sustained.
Information query
