Invention Application
- Patent Title: METHODS OF GENERATING OLIGODENDROCYTES
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Application No.: US17618541Application Date: 2020-06-11
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Publication No.: US20220233477A1Publication Date: 2022-07-28
- Inventor: Benjamin Eithan REUBINOFF , Etti BEN-SHUSHAN
- Applicant: Hadasit Medical Research Services and Development Ltd.
- Applicant Address: IL Jerusalem
- Assignee: Hadasit Medical Research Services and Development Ltd.
- Current Assignee: Hadasit Medical Research Services and Development Ltd.
- Current Assignee Address: IL Jerusalem
- International Application: PCT/IL2020/050652 WO 20200611
- Main IPC: A61K31/166
- IPC: A61K31/166 ; C12N5/079 ; A61P9/10 ; A61P37/06 ; A61P25/28
Abstract:
A method of generating human mature oligodendrocytes is disclosed. The method comprises contacting a cell population which comprises human pre-oligodendrocytes with an inhibitor of the MAPK/ERK pathway under conditions that allow the pre-oligodendrocytes to differentiate into mature oligodendrocytes. Use of the MAPK/ERK pathway inhibitor for treating diseases is also disclosed.
Information query
