Invention Application
- Patent Title: SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS
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Application No.: US17168574Application Date: 2021-02-05
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Publication No.: US20220356166A1Publication Date: 2022-11-10
- Inventor: Pravin L. Kotian , Yarlagadda S. Babu , Weihe Zhang , Peng-Cheng Lu , Minwan Wu , Wei Lv , Trung Xuan Nguyen , Zhao Dang , Venkat R. Chintareddy , V. Satish Kumar , Krishnan Raman
- Applicant: BioCryst Pharmaceuticals, Inc.
- Applicant Address: US NC Durham
- Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee Address: US NC Durham
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07D209/12 ; C07D261/20 ; C07D307/80 ; C07D333/64 ; C07D401/12 ; C07D405/10
Abstract:
Disclosed are compounds of formulae I and II, and pharmaceutically acceptable salts and prodrugs thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.
Public/Granted literature
- US11708347B2 Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors Public/Granted day:2023-07-25
Information query
