Invention Application
- Patent Title: RENAL TARGETING-TYPE DRUG DELIVERY CARRIER HAVING EXCELLENT BIODEGRABILITY
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Application No.: US17624112Application Date: 2020-07-01
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Publication No.: US20220362278A1Publication Date: 2022-11-17
- Inventor: Hidemasa Katsumi , Akira Yamamoto
- Applicant: KYOTO PHARMACEUTICAL UNIVERSITY
- Applicant Address: JP Kyoto-shi, Kyoto
- Assignee: KYOTO PHARMACEUTICAL UNIVERSITY
- Current Assignee: KYOTO PHARMACEUTICAL UNIVERSITY
- Current Assignee Address: JP Kyoto-shi, Kyoto
- Priority: JP2019-123540 20190702
- International Application: PCT/JP2020/026618 WO 20200701
- Main IPC: A61K31/7088
- IPC: A61K31/7088 ; A61K49/00 ; A61K47/42 ; A61K47/64 ; A61P13/12

Abstract:
The present invention aims to provide a carrier for drug delivery that selectively accumulates in the kidney in the body, and shows high biodegradability and drug releasability in the kidney. The present invention relates to a compound in which a carbonyl group of serine is linked directly or via a linker to terminal amino group of linear polylysine, compound carrier for delivery, and a medicament for the diagnosis, prophylaxis, or treatment of a renal disease, containing the carrier for drug delivery, and a drug bound to the carrier directly or via a linker or encapsulated therein.
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