Invention Application
- Patent Title: MULTISPECIFIC BINDERS OF TGFBeta-SUPERFAMILY LIGANDS AND USES THEREOF
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Application No.: US17052785Application Date: 2019-05-02
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Publication No.: US20220372107A1Publication Date: 2022-11-24
- Inventor: Ravindra Kumar , Dianne S. Sako , Roselyne Castonguay , Tzu-Hsing Kuo
- Applicant: Acceleron Pharma Inc.
- Applicant Address: US MA Cambridge
- Assignee: Acceleron Pharma Inc.
- Current Assignee: Acceleron Pharma Inc.
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2019/030469 WO 20190502
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K14/71 ; C07K16/22
Abstract:
In certain aspects, the disclosure provides multispecific binders (e.g., ActRIIA:TβRII heteromultimers comprising an ActRIIA polypeptide and a TfiRU polypeptide). The disclosure further provides that such multispecific binders (e.g., ActRIIA:TβRII heteromultimer) may be used to treat various disorders or conditions.
Public/Granted literature
- US12103959B2 Multispecific binders of TGFBeta-superfamily ligands and uses thereof Public/Granted day:2024-10-01
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