Invention Application
- Patent Title: MESSENGER RNA COMPRISING FUNCTIONAL RNA ELEMENTS AND USES THEREOF
-
Application No.: US17618779Application Date: 2020-06-24
-
Publication No.: US20220387628A1Publication Date: 2022-12-08
- Inventor: Ruchi JAIN , David REID , Vladimir PRESNYAK , Alicia BICKNELL , Caroline KÖHRER
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2020/039365 WO 20200624
- Main IPC: A61K48/00
- IPC: A61K48/00
Abstract:
The present disclosure provides messenger RNAs (mRNAs) having chemical and/or structural modifications, including RNA elements and/or modified nucleotides, which provide desirable regulation of mRNA localization, stability, and/or translation to yield increased mRNA expression and activity of an encoded polypeptide.
Information query
