Invention Application
- Patent Title: THERMOSTABLE POLYMERASE INHIBITOR COMPOSITIONS AND METHODS
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Application No.: US17687473Application Date: 2022-03-04
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Publication No.: US20220389427A1Publication Date: 2022-12-08
- Inventor: Sergey G. Lokhov , Alexander A. Gall , Vera Baraznenok , Ekaterina V. Viazovkina , Irina Shishkina , David H. Persing
- Applicant: Cepheid
- Applicant Address: US CA Sunnyvale
- Assignee: Cepheid
- Current Assignee: Cepheid
- Current Assignee Address: US CA Sunnyvale
- Main IPC: C12N15/115
- IPC: C12N15/115 ; C12Q1/6853 ; C12Q1/686
Abstract:
The present disclosure relates to aptamers for temperature-dependent reversible inhibition of thermostable polymerase activity in order to improve sensitivity and specificity of various reactions and assays involving hot start polynucleotide synthesis. Methods for use of the aptamers and related compositions and kits are also provided.
Information query
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