Invention Publication
- Patent Title: METHODS OF TREATMENT OF CORONAVIRUS-INDUCED INFLAMMATION CONDITIONS
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Application No.: US17917022Application Date: 2021-04-05
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Publication No.: US20230149345A1Publication Date: 2023-05-18
- Inventor: David R. Elmaleh , Ana Griciuc , Ghazaleh Sadri-Vakili , Sabrina Paganoni , Rudolph E. Tanzi
- Applicant: The General Hospital Corporation
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- International Application: PCT/US21/25746 2021.04.05
- Date entered country: 2022-10-05
- Main IPC: A61K31/353
- IPC: A61K31/353 ; A61P29/00 ; A61P31/14 ; A61P11/00 ; A61K45/06

Abstract:
The present disclosure relates to a method of treating one or more inflammation conditions induced by a coronavirus infection in a subject in need thereof, comprising administering a pharmaceutical composition comprising a compound of Formula I or Formula II, wherein R1 is halogen, OH, or —OC(O)C1-5alkyl, R2 and R3 are each independently selected from CO2R4 and CH2OR5; R4 is Li, Na, K, H, C1-5-alkyl, or —CH2CO(C1-5alkyl); and R5 is H or —C(O)(C1-5alkyl), or a pharmaceutically acceptable salt thereof.
Information query
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