A display substrate and a display device are disclosed. The display substrate includes: a a transition region, located between a first display region and a second display region, the first display region, the second display region and the transition region are provided with a plurality of pixels, the plurality of pixels are arranged in an array in the first direction and a second direction intersecting with the first direction, a pixel per inch (PPI) of the first display region is greater than a PPI of the second display region and a PPI of the transition region, the transition region is further provided with a row driving circuit, the row driving circuit is configured to drive the plurality of pixels in the first display region, the second display region and the transition region by rows.